Vic and Melinda Van Allen are a couple in the small town of Little Wesley. Their loveless marriage is held together only by a precarious arrangement whereby, in order to avoid the messiness of divorce, Melinda is allowed to take any number of lovers as long as she does not desert her family. Vic becomes fascinated with the unsolved murder of one of Melinda's former lovers, Malcolm McRae, and, in order to successfully drive away her current fling, takes credit for the killing. When the real...

Two New Orleans paramedics' lives are ripped apart after they encounter a series of horrific deaths linked to a designer drug with bizarre, otherworldly effects.

Tim Blake Nelson (The Ballad of Buster Scruggs) is a man who's safe and comfortable and bored to death with his life. In his state of despair, he looks to classic stories for inspiration. Awakened by the tales of yore, he anoints himself as Don Quixote to find adventure, fame and glory that will make his life worthwhile - all while never leaving his one-mile square neighborhood.